Aprea Therapeutics secured $51M Series B financing.

Aprea AB, a Stockholm, Sweden-based clinical-stage biotechnology company developing novel anticancer therapies targeting the tumor suppressor protein p53, today announced that it has completed a Series B financing round, raising EUR 46 million (approximately USD 51 million).

The international syndicate was co-led by Versant Ventures and 5AM Ventures, with participation by Sectoral Asset Management. HealthCap acted as the local lead investor. Aprea's main shareholder is KDev Investments AB, an investment vehicle owned by Karolinska Development AB (Nasdaq Stockholm: KDEV) and Rosetta Capital Ltd.

The funds will be used to advance the clinical development of lead program APR-246, a first-in-class anticancer compound reactivating the tumor suppressor protein p53. Aprea is completing the Phase Ib part of a Phase Ib/II clinical study in high-grade serous ovarian cancer with APR-246 and plans to initiate the randomized Phase II part of the trial shortly. In addition, further exploratory trials in other cancer indications, including both solid and hematological tumors, are planned. The Company will also establish its strategic leadership team in the U.S.

Aprea AB is a Swedish biotech company focusing on the discovery and development of novel anticancer compounds reactivating the tumor suppressor protein p53. The Company's lead program, APR-246, is a first-in-class small molecule drug candidate in clinical development.